Syphilis Tests: Understanding Types, Accuracy, and Costs
Introduction: Why Syphilis Testing Matters
Syphilis testing is a crucial component of sexual health management, especially given the recent resurgence of this bacterial infection worldwide. Early detection through proper testing not only ensures effective treatment but also prevents serious long-term complications and stops further transmission. This comprehensive guide covers everything you need to know about syphilis tests, including different testing methods, their accuracy, costs, and what to expect during the testing process.
Types of Syphilis Tests
1. Nontreponemal Tests
These tests detect antibodies that are not specific to syphilis but are often produced in response to the infection.
Common Nontreponemal Tests:
- RPR (Rapid Plasma Reagin)
- VDRL (Venereal Disease Research Laboratory)
Best Used For:
- Initial screening
- Monitoring treatment response
- Detecting disease activity
2. Treponemal Tests
These tests detect antibodies specific to Treponema pallidum, the bacteria that causes syphilis.
Common Treponemal Tests:
- FTA-ABS (Fluorescent Treponemal Antibody Absorption)
- TP-PA (Treponema pallidum Particle Aggregation)
- EIA/CIA (Enzyme Immunoassay/Chemiluminescence Immunoassay)
Best Used For:
- Confirming diagnosis after positive screening test
- Detecting past or current infections
3. Direct Detection Methods
These methods directly identify the syphilis bacteria.
Darkfield Microscopy(rare in Hong Kong):
- Examines fluid from sores under special microscope
- Requires experienced technician
- Immediate results when available
PCR Tests:
- Detects bacterial DNA
- Particularly useful for early primary syphilis
- Highly specific
- Swab sample is preferred
Cost of Syphilis Testing
We provide express syphilis test reports with a reporting time of 4-16 hours (if infected) so that you can receive syphilis treatment as soon as possible.
- Treponema pallidum antibody (TP) test : $250
- Syphilis RPR Test : $150
- Syphilis DNA test (Swab sample from sores) : $690
| Item | Price | Window Period | Sample | Turnaround Time |
|---|---|---|---|---|
| Syphilis Antibody | $250 | 14 days | Blood | 8-24 hours |
| Syphilis RPR | $150 | 14 days | Blood | 8-24 hours |
| Syphilis Quick Test* | $240 | 45 days | Blood | 15 mins |
| Syphilis DNA Test | $690 | 7 days | Swab | 8-24 hours |
*Syphilis Quick Test do not provide a test report.
Understanding Your Results
When both Syphilis RPR test and Antibody test get positive, infection is confirmed, doctor consultation is advised immediately. You may look at the results interpretation table below.
Syphilis DNA PCR test
A swab is extracted with a sample from the ulcer. This test is only suitable for people with suspected syphilis ulcer symptoms. When you got PCR test positive, you are infected.
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